Publicly Offered Research (2023~2024)

A01: Measurement of “Weak Interactions” for Material Symbiosis

  • Yutaka Kofuku
    Graduate School of Pharmaceutical Sciences, The University of Tokyo
    “NMR investigation of signal tranduction mechanism mediated by weak ligand-receptor interaction”
  • Akio Kitao
    School of Life Science and Technology, Tokyo Institute of Technology
    “Quantitative prediction of interactions involved in material symbiosis using the latest simulation technology”
  • Tomohiro Hayashi
    School of Materials and Chemical Technology, Tokyo Institute of Technology
    “Atomic resolution mapping of binding free energies to explore molecular recognition pathways”
  • Yuto Honda
    Institute of Innovative Research, Tokyo Institute of Technology
    “Development of multivalent interaction observation technique by combining spectroscopic and microscopic methods”
  • Masato Katahira
    Kyoto University Institute of Advanced Energy
    “Development and application of methods for measuring and analyzing interactions in living human cells in which material symbiosis has been established”
  • Yukihiro Okamoto
    Graduate School of Engineering Science, Osaka University
    “Research for weak interaction analysis between nanodomains by electrophoresis in lipid nanomembrane”
  • Yusuke V. Morimoto
    Faculty of Computer Science and Systems Engineering, Kyushu Institute of Technology
    “Measurement of cell dynamics dependent on local pH in the vicinity of the cell membrane”
  • Shuya Fukai
    Faculty of Science, Kyoto University
    “Analysis of the selectivity of less stable interactions between synaptic cell adhesion molecules and scaffold proteins by fluorescence imaging”

A02: Identification of Symbiotic Parametars between Materials and Biomolecules/Living cells

  • Shinichi Sato
    Frontier Research Institute for Interdisciplinary Sciences, Tohoku University
    “Comprehensive analysis of binding proteins in symbiotic materials utilizing proximity labeling”
  • Kazumitsu Onizuka
    IMRAM, Tohoku University
    “Large-scale analysis of nucleic acid-related molecular interactions and its application to material symbiosis research”
  • Tomoko Hashimoto
    Faculty of Textile Science and Technology, Shinshu University
    “Analysis of material symbiosis parameters of polymeric biomaterials with living organisms”
  • Yukiko Kamiya
    Kobe Pharmaceutical University
    “Investigation of intracellular interaction that control the safety and toxicity of artificial nucleic acids”
  • 研究代表者
    Nobuyuki Morimoto
    Faculty of Materials for Energy, Shimane University
    “Elucidation and parameterization of weak interactions between materials and cell membranes”

A03: Design and Development of Novel Symbiotic Materials

  • Masatoshi Maeki
    Faculty of Engineering, Hokkaido University
    “Development of virus-mimetic exosomes for material symbiosis”
  • Satoshi Okada
    IIR, Tokyo Institute of Technology
    “Development of Immunomodulation via Calcium-Sensing Receptors by Magnetic Fields”
  • Yusuke Kawamoto
    Graduate School of Pharmaceutical Sciences, Kyoto University
    “Development of novel nucleic acid medicines utilizing hydrophobic intereactions with Toll-like receptors”
  • Soyoung Park
    Immunology Frontier Research Center, Osaka University
    “Development of Immunomodulator based on Amino acid-Nucleic acid Hybrids”
  • Eiji Yuba
    Graduate School of Engineering, Osaka Metropolitan University
    “Preparation of functional lipid nanoparticles for induction of regulatory B cells and their application to the treatment of autoimmune diseases”
  • Shin-ichi Yusa
    Graduate School of Engineering, University of Hyogo
    “Interaction between polyampholytes and cell membranes capable of switching charge balance by light”
  • Tadahiro Yamashita
    Faculty of Science and Technology, Keio University
    “Engineering scaffold curvature and adhesive ligand to control cellular phenotype”