A01: Measurement of “Weak Interactions” for Material Symbiosis

• 
  Yutaka Kofuku
  Graduate School of Pharmaceutical Sciences, The University of Tokyo
  “NMR investigation of signal tranduction mechanism mediated by weak ligand-receptor interaction”
• 
  Akio Kitao
  School of Life Science and Technology, Tokyo Institute of Technology
  “Quantitative prediction of interactions involved in material symbiosis using the latest simulation technology”
• 
  Tomohiro Hayashi
  School of Materials and Chemical Technology, Tokyo Institute of Technology
  “Atomic resolution mapping of binding free energies to explore molecular recognition pathways”
• 
  Yuto Honda
  Institute of Innovative Research, Tokyo Institute of Technology
  “Development of multivalent interaction observation technique by combining spectroscopic and microscopic methods”
• 
  Masato Katahira
  Kyoto University Institute of Advanced Energy
  “Development and application of methods for measuring and analyzing interactions in living human cells in which material symbiosis has been established”
• 
  Yukihiro Okamoto
  Graduate School of Engineering Science, Osaka University
  “Research for weak interaction analysis between nanodomains by electrophoresis in lipid nanomembrane”
  
• 
  Yusuke V. Morimoto
  Faculty of Computer Science and Systems Engineering,　Kyushu Institute of Technology
  “Measurement of cell dynamics dependent on local pH in the vicinity of the cell membrane”
• 
  Shuya Fukai
  Faculty of Science, Kyoto University
  “Analysis of the selectivity of less stable interactions between synaptic cell adhesion molecules and scaffold proteins by fluorescence imaging”

A02: Identification of Symbiotic Parametars between Materials and Biomolecules/Living cells

• 
  Shinichi Sato
  Frontier Research Institute for Interdisciplinary Sciences, Tohoku University
  “Comprehensive analysis of binding proteins in symbiotic materials utilizing proximity labeling”
• 
  Kazumitsu Onizuka
  IMRAM, Tohoku University
  “Large-scale analysis of nucleic acid-related molecular interactions and its application to material symbiosis research”
• 
  Tomoko Hashimoto
  Faculty of Textile Science and Technology, Shinshu University
  “Analysis of material symbiosis parameters of polymeric biomaterials with living organisms”
• 
  Yukiko Kamiya
  Kobe Pharmaceutical University
  “Investigation of intracellular interaction that control the safety and toxicity of artificial nucleic acids”
• 
  研究代表者
  Nobuyuki Morimoto
  Faculty of Materials for Energy， Shimane University
  “Elucidation and parameterization of weak interactions between materials and cell membranes”

A03: Design and Development of Novel Symbiotic Materials

• 
  Masatoshi Maeki
  Faculty of Engineering, Hokkaido University
  “Development of virus-mimetic exosomes for material symbiosis”
• 
  Satoshi Okada
  IIR, Tokyo Institute of Technology
  “Development of Immunomodulation via Calcium-Sensing Receptors by Magnetic Fields”
• 
  Soyoung Park
  Immunology Frontier Research Center, Osaka University
  “Development of Immunomodulator based on Amino acid-Nucleic acid Hybrids”
• 
  Eiji Yuba
  Graduate School of Engineering, Osaka Metropolitan University
  “Preparation of functional lipid nanoparticles for induction of regulatory B cells and their application to the treatment of autoimmune diseases”
• 
  Shin-ichi Yusa
  Graduate School of Engineering, University of Hyogo
  “Interaction between polyampholytes and cell membranes capable of switching charge balance by light”
• 
  Tadahiro Yamashita
  Faculty of Science and Technology, Keio University
  “Engineering scaffold curvature and adhesive ligand to control cellular phenotype”

Collaborators

• 

  Yusuke Kawamoto
  NATiAS Inc.